Classification of <i>?</i>-Thalassemia Carriers From Red Blood Cell Indices Using Ensemble Classifier

Detection of β-Thalassemia Carriers by Red Cell Parameters Obtained from Automatic Counters using Mathematical Formulas

Background β-thalassemia major is a severe disease with high morbidity. The world prevalence of carriers is around 1.5-7%. The present study aimed to find a reliable formula for detecting β-thalassemia carriers using an extensive database of more than 22,000 samples obtained from a homogeneous population of childbearing age women with 3161 (13.6%) of β-thalassemia carriers and to check previous...

Dynamic classifier ensemble using classification confidence

How to combine the outputs from base classifiers is a key issue in ensemble learning. This paper presents a dynamic classifier ensemble method termed as DCE-CC. It dynamically selects a subset of classifiers for test samples according to classification confidence. The weights of base classifiers are learned by optimization of margin distribution on the training set, and the ordered aggregation ...

Thalassemia screening based on red cell indices in the Chinese.

Diagnostic reliability check of red cell indices in differentiating Iron Deficiency Anemia (IDA) from Beta Thalassemia Minor (BTT)

Introduction: Iron deficiency anemia and beta-thalassemia trait are the two most common causes of hypochromic microcytic anemia. There are some discriminating functions (DFs) formula to differentiate these two conditions based on RBC's indices which would be compared the validity of the 14 various indices in this study. Correspond...

measuring viscoelastic properties of Red Blood Cell using optical tweezers

Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of s...